GMP-Certified Solutions for Pharma, Biotech & Cosmetics
Biotts offers comprehensive, GMP-compliant research and development services tailored to the needs of pharmaceutical, biotechnology, cosmetic, and dietary supplements companies. Backed by a multidisciplinary team and GMP-certified laboratories, we support projects from formulation design to analytical validation. Whether you’re looking for a reliable lab partner or a complete R&D extension team — we’re here to deliver.
We partner with businesses across multiple regulated and innovation-driven sectors:
All services are performed in-house in our modern, GMP-compliant facility equipped with:
At our GMP-certified research and development facility, we deliver high-quality, tailored R&D services for the pharmaceutical, biotechnology, diet supplementary and cosmetics industries.
Early Drug Development Phase
ADME/DMPK profiling, in vitro/in vivo pharmacology, synthetic and medicinal chemistry, and toxicology studies.
Formulation and Drug Form Development
Expertise in small molecule and biologics drug form development, including analytical CMC support and custom dosage form design.
Stability & Release Testing
ICH-compliant long-term and accelerated stability studies; dissolution and permeation testing across a wide range of barriers, media, and conditions (USP, Ph. Eur., Franz diffusion cells).
Advanced Analytical Services
Method development and validation (ICH Q2), bioequivalence studies (IVIVC), and microbiological testing.
Process Development & Scale-Up
Optimization, tech transfer, and GMP manufacturing of preclinical and clinical batches.
CDMO Services
Comprehensive support from lab-scale prototypes to GMP production, including QA/QC, project management, and regulatory documentation.
Development of tailored formulas and recipes for clients
Composition analysis and functional testing
Composition analysis: determination of vitamins (A, D, E, B-complex), minerals (Mg, Zn, Se), plant extracts (HPLC fingerprint)
Functional testing: tests of ingredient bioavailability (in vitro – digestion model), determination of biological activity and antioxidant testing (ORAC, DPPH).
Product safety
Determination of contaminants: heavy metals (Hg, Pb, Cd, As), mycotoxins, pesticides (GC-MS – additional service) and microbiological testing: tests (LOD, Salmonella) – optionally supplemented with additional controls.
Regulatory support and production
Preparation of documentation for GIS (Chief Sanitary Inspectorate), verification of health claim, comparative studies (against a reference product). Prototype manufacturing and production of prototypes (capsules, tablets, liquids, patches).
Formula Development and Custom Formulation
We specialize in developing innovative and effective cosmetic formulas and recipes tailored to your specific needs.
Penetration and Efficacy Testing
Franz Cell Diffusion Studies: permeation kinetics, local bioavailability, depot effect
Research Models: full-thickness and split-thickness skin models, artificial membrane models
Formulation Analysis and Stability
Instrumental Analysis:
Cosmetic Recipe Development
We specialize in creating unique cosmetic recipes, with a focus on natural raw materials and minimizing synthetic ingredients.
Regulatory Support and Product Registration
Documentation and Compliance: GMP documentation, EU Cosmetics Regulation compliance, finished product registration
Looking for a dependable R&D and lab partner? Let’s discuss your project — no matter how early or advanced the stage.